By Last Name
BU DechaoAssociate Professor
Research Areas:
Medical Multimodal Artificial Intelligence;Cancer Intelligent Decision-Making
Department:
Research Center For Ubiquitous Computing Systems
Tutor Category:
Contact:
budechao@ict.ac.cn
Personal Page:
https://scholar.google.com/citations?user=o-CZlyYAAAAJ
Dr. Dechao is associate professor of Institute of Computing Science, Chinese Academy of Sciences, Master's supervisor, engaged in research on artificial intelligence on multimodality data in cancer, Highly Cited Researcher in the field of Biology and Biochemistry - 2022. He published 12 SCI papers as the first author, among which 6 papers have an impact factor of more than 10, 1 paper was cited more than 300 times, and 2 were rewarded ESI highly cited papers. His leading projects include 1 National Key R&D Program of China, 2 sub-projects of National Key R&D Program of China, 1 Youth Fund project of the Natural Science Foundation, 1 Beijing Key Research and Development Project of natural science.
Publications
1. Bu D#, Luo H#, Huo P, et al. KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis. Nucleic Acids Res. 2021;49(W1):W317-W325. doi:10.1093/nar/gkab447. (IF=19.2, ESI highly cited)
2. Cheng Y#, Bu D#.et al. Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer. Journal of advanced research, S2090-1232(22)00248-X. (IF=12.8)
3. Ning J#, Ye Y#, Bu D#, et al. Imbalance of TGF-β1/BMP-7 pathways induced by M2-polarized macrophages promotes hepatocellular carcinoma aggressiveness. Mol Ther. 2021;29(6):2067-2087. doi:10.1016/j.ymthe.2021.02.016. (IF=12.9, co-first author)
4. Zhang Y#, Bu D#, Huo P, et al. ncFANs v2.0: an integrative platform for functional annotation of non-coding RNAs. Nucleic Acids Res. 2021;49(W1):W459-W468. doi:10.1093/nar/gkab435. (IF=19.2, co-first author)
5. Bu D#, Yu K#, Sun S, et al. NONCODE v3.0: integrative annotation of long noncoding RNAs. Nucleic Acids Res. 2012;40(Database issue):D210-D215. doi:10.1093/nar/gkr1175. (IF=19.2, ESI highly cited)
6. Zhao G, Bu D#, Liu C, et al. CloudLCA: finding the lowest common ancestor in metagenome analysis using cloud computing. Protein Cell. 2012;3(2):148-152. doi:10.1007/s13238-012-2015-8. (IF=14.9, co-first author)
7. Luo H, Bu D#, Sun L, Fang S, Liu Z, Zhao Y. Identification and function annotation of long intervening noncoding RNAs. Brief Bioinform. 2017;18(5):789-797. doi:10.1093/bib/bbw046. (IF=11.6, co-first author)
8. Bu D#, Xia Y#, Zhang J#, Cao W#, et al. FangNet: Mining herb hidden knowledge from TCM clinical effective formulas using structure network algorithm. Comput Struct Biotechnol J. 2020;19:62-71. Published 2020 Dec 4. doi:10.1016/j.csbj.2020.11.036. (IF=7.3)
9. Bu D#, Peng S#, Luo H, et al. “From Big Data to Knowledge in Precision Medicine” in Precision medicine and cancer immunology in China. Science. 2018 Feb . (IF=47.7, supplement, review)
10. Luo H#, Bu D#, Shao L, et al. Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity [published online ahead of print, 2021 Jul 17]. Genomics Proteomics Bioinformatics. 2021;S1672-0229(21)00155-8. doi:10.1016/j.gpb.2021.02.006. (IF=7.7, co-first author)
11. Bu D#, Luo H#, Jiao F, et al. Evolutionary annotation of conserved long non-coding RNAs in major mammalian species. Sci China Life Sci. 2015;58(8):787-798. doi:10.1007/s11427-015-4881-9. (IF=6.0)
12. Wang R#, Yang Y#, Sheng M#, Bu D#, et al. Phenotype-Genotype Association Analysis of ACTH-Secreting Pituitary Adenoma and Its Molecular Link to Patient Osteoporosis. Int J Mol Sci. 2016;17(10):1654. (IF=5.9, co-first author)
Projects:
1. National Key R&D Program of China “Research and development of cross analysis algorithm and intelligent mining technology based on multi-modal information fusion”
2. National Key R&D Program of China "Biological Big Data Management and Analysis Key technology and system" project - "Biological Data intelligent Management and analysis and retrieval System" sub-project leader ;
3. National Key R&D Program of China "Research on the Experience Inheritance and Innovation of Famous Traditional Chinese Medicine Based on the combination of Daoshu and multiple fusion methods" project - "Construction of an integrated platform for the experience Research and Promotion of Famous Traditional Chinese Medicine" project, leader of the sub-project;
4. National Natural Science Foundation of China. Homology Prediction Algorithm of Long noncoding genes based on Comparative Genomics and its conservation of sequence structure and expression
5. Beijing Key Research and Development Project of natural science “Optimization and validation of TheraRNA, an mRNA vaccine nucleic acid sequence design platform”